Bio-Connect

anti-CD24 antibody [SN3] (FITC)

Research Use Only
ARG65541
Arigo Biolaboratories
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityHuman
TargetCD24
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-CD24 antibody [SN3] (FITC)
  • Delivery Days Customer
    23
  • Applications
    Flow Cytometry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    SN3
  • Conjugate
    FITC
  • Gene ID100133941
  • Target name
    CD24
  • Target description
    CD24 molecule
  • Target synonyms
    CD24 antigen (small cell lung carcinoma cluster 4 antigen); CD24A; signal transducer CD24
  • Host
    Mouse
  • Isotype
    IgG1
  • Scientific Description
    CD24, also known as heat-stable antigen (HSA) or nectadorin, is a small mucin-like GPI-anchored extracellular membrane glycoprotein expressed on several cell types, including B cells. When B cells are activated and induced to further maturation, however, CD24 begins to disappear. CD24 seems to act as a gate-keeper for lipid rafts, thereby regulating the activity of integrins and other proteins such as the chemokine receptor CXCR4; it is also a ligand for P-selectin. CD24 triggering induces apoptosis of B cell precursors but not in mature resting B cells, where it instead inhibits their ability to proliferate in response to activation. CD24 expression is associated with invasiveness and poorer prognosis of carcinomas and is a marker of exosomes secreted into urine and amniotic fluid.
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203