Anti-CD24 [G7]

Absolute Antibody

Anti-CD24 [G7]

7

This antibody binds human CD24.

This antibody showed specific binding affinity to recombinant human CD24 but not to unrelated recombinant Fc in a western blot. The binding specifity of G7 towards CD24 was also confirmed with competitive ELISA. Flow cytometric assay was carried out to assess the affinities of G7 to native CD24 expressed on Huh7 and HT29 cells with HCT116 cells as control. G7mAb demonstrated significant binding to both Huh7 and HT29 cells with rates 52.9% and 41.3% respectively. This antibody was also used in immunohistochemical staining of tumor samples from Huh7 xenograft nude mice (PMID: 26255089).

Flow Cytometry, Western Blot, ELISA, ImmunoHistoChemistry

WB, ELISA, FC, IHC

Research Use Only

Monoclonal

G7

CD24

CD24 molecule

CD24 antigen (small cell lung carcinoma cluster 4 antigen); CD24A; signal transducer CD24

Human

IgG1

Signal transducer CD24

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Human

Human

The original antibody was generated by immunizing BALB/c mice with a CD24 core region polypeptide and hemocyanin KLH conjugate (CD24-KLH) as immunogen.

-20°C,2°C to 8°C

12352203