anti-CD253 / TRAIL antibody [2E5] (PE)

Arigo Biolaboratories

anti-CD253 / TRAIL antibody [2E5] (PE)

23

Flow Cytometry

Research Use Only

Monoclonal

2E5

0.1 mg/ml

RPE

TNFSF10

TNF superfamily member 10

Apo-2 ligand; APO2L; Apo-2L; CD253; chemokine tumor necrosis factor ligand superfamily member 10; TL2; TNF-related apoptosis inducing ligand TRAIL; TNLG6A; TRAIL; tumor necrosis factor (ligand) family, member 10; tumor necrosis factor (ligand) superfamily, member 10; tumor necrosis factor apoptosis-inducing ligand splice variant delta; tumor necrosis factor ligand 6A; tumor necrosis factor ligand superfamily member 10; tumor necrosis factor superfamily member 10

Mouse

IgG1

Human CD253 / TRAIL (TNF-Related Apoptosis Inducing Ligand), also called Apo2, is a type II membrane protein from the TNF family. TRAIL is a cytotoxic protein which activates rapid apoptosis in tumor cells, but not in normal cells. TRAIL-induced apotosis, is achieved through binding to two dealth-signaling receptors, DR4 (CD261 / TRAIL-R1) and DR5 (CD262 / TRAIL-R2).

Human

2°C to 8°C

12352203