Anti-CD257 (BAFF) [H1104-30]

Absolute Antibody

Anti-CD257 (BAFF) [H1104-30]

9

This antibody binds human BAFF protein and cross reacts with cynomolgus monkey BAFF protein and weakly reacts with mouse BLyS. B-cell-activating factor (BAFF/CD257) is a cytokine belonging to the tumour-necrosis factor (TNF) family. This cytokine binds to

The binding affinity of the IgG version of this antibody for human BLyS-His protein was reported to be Kd= 0.3023 nM. The binding reactivity of this antibody for human, mouse and cynomolgus monkey BLyS protein was done using ELISA. This antibody does not show any cross reactivity with other members of the TNF family. In vitro, this antibody can block the binding between BLyS and its receptor and also inhibits the proliferation of mouse splenocytes stimulated by BLyS (WO2014139425).

ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

H1104-30

TNFSF13B

TNF superfamily member 13b

ApoL related ligand TALL-1; BAFF; B-cell-activating factor; B-lymphocyte stimulator; BLYS; CD257; delta BAFF; Delta4 BAFF; dendritic cell-derived TNF-like molecule; DTL; epididymis secretory sperm binding protein; TALL1; TALL-1; THANK; TNF and ApoL-related leukocyte expressed ligand 1; TNF homolog that activates apoptosis; TNFSF20; TNLG7A; tumor necrosis factor (ligand) superfamily, member 13b; tumor necrosis factor (ligand) superfamily, member 20; tumor necrosis factor ligand 7A; tumor necrosis factor ligand superfamily member 13B; tumor necrosis factor superfamily member 13b; tumor necrosis factor-like protein ZTNF4; ZTNF4

Rabbit

IgG

Tumor necrosis factor ligand superfamily member 13B

Human, Monkey, Mouse

-20°C,2°C to 8°C

12352203