anti-CD263 / TRAIL R3 antibody [TRAIL-R3-02] (PE)

Arigo Biolaboratories

anti-CD263 / TRAIL R3 antibody [TRAIL-R3-02] (PE)

23

Flow Cytometry

Research Use Only

Monoclonal

TRAIL-R3-02

0.1 mg/ml

RPE

TNFRSF10C

TNF receptor superfamily member 10c

antagonist decoy receptor for TRAIL/Apo-2L; CD263; cytotoxic TRAIL receptor-3; DCR1; DCR1-TNFR; decoy receptor 1; decoy TRAIL receptor without death domain; LIT; lymphocyte inhibitor of TRAIL; TNF-related apoptosis-inducing ligand receptor 3; TRAILR3; TRAIL-R3; TRID; tumor necrosis factor receptor superfamily member 10C; tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain

Mouse

IgG1

TRAIL-R3 (CD263, TR3, DcR1, LIT, TRID), expressed mainly on neutrophils, belongs to receptors of TRAIL, a TNF-like membrane cytotoxic protein that induces apoptosis in many tumour cells, but not in normal cells. TRAIL-R3, however, is a GPI-anchored protein that lacks cytoplasmic death domain, thus it is unable to induce apoptosis and serves as a negative regulator of apoptotic signaling by competing for binding of TRAIL with death receptor 5 (DR5).

2°C to 8°C

12352203