anti-CD276 / B7-H3 antibody [MJ8] (PE)
ARG23658
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityMouse
TargetCd276
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-CD276 / B7-H3 antibody [MJ8] (PE)
- Delivery Days Customer23
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDMJ8
- ConjugateRPE
- Gene ID102657
- Target nameCd276
- Target descriptionCD276 antigen
- Target synonyms6030411F23Rik; AU016588; B7 homolog 3; B7h3; B7-H3; B7RP; B7RP-2; CD276 antigen; costimulatory molecule
- HostRat
- IsotypeIgG2b
- Scientific DescriptionThe protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3 UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
- ReactivityMouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203