Anti-CD28 [JJ316]

Absolute Antibody

Anti-CD28 [JJ316]

9

Recognises rat CD28 and can trigger T-cell proliferation in vitro and in vivo.

This antibody binds rat CD28 and can convey as a co-stimulatory signal. At 100-1000-fold higher concentration than required for co-stimulation JJ316 (unlike the clone JJ319 marketed by competitors (see Tacke et al. 1997)) can induce proliferation of all T-cell subsets without TCR engagement.

Flow Cytometry, ImmunoFluorescence, ImmunoHistoChemistry, Other Application

Research Use Only

Monoclonal

JJ316

Cd28

Cd28 molecule

CD28 antigen; CD28RNA; T-cell-specific surface glycoprotein CD28

Rat

IgG2b

T-cell-specific surface glycoprotein CD28

This is a chimeric antibody created to reduce immunogenicity during in vivo applications.

Rat

-20°C,2°C to 8°C

12352203