anti-CD284 / TLR4 antibody
ARG20469
ApplicationsWestern Blot
Product group Antibodies
ReactivityRat
TargetTlr4
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-CD284 / TLR4 antibody
- Delivery Days Customer23
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5 mg/ml
- ConjugateUnconjugated
- Gene ID29260
- Target nameTlr4
- Target descriptiontoll-like receptor 4
- Target synonymstoll4; toll-like receptor 4
- HostRabbit
- IsotypeIgG
- Scientific DescriptionTLR4 (Toll-like receptor 4) is a mammalain homologue of the Drosophila toll protein. The human TLR4 is a type-1 transmembrane protein containing 799 amino acid residues. The extracellular domain has leucine-rich repeats and the intracellular domain is similar to that of IL-1 receptor. TLR4 is a receptor for lipopolysaccharide (LPS). In mice that are genetically tolerant to endotoxin, mutations have been identified in the intracellular domain of TLR4 that abolish LPS responsiveness. TLR4 uses a mechanism similar to that of the IL-1 receptor for signal transduction that leads to activation of NF-kB.
- ReactivityRat
- Storage Instruction-20°C
- UNSPSC12352203