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anti-CD284 / TLR4 antibody

ARG20469
Arigo Biolaboratories
ApplicationsWestern Blot
Product group Antibodies
ReactivityRat
TargetTlr4
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-CD284 / TLR4 antibody
  • Delivery Days Customer
    23
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.5 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID29260
  • Target name
    Tlr4
  • Target description
    toll-like receptor 4
  • Target synonyms
    toll4; toll-like receptor 4
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    TLR4 (Toll-like receptor 4) is a mammalain homologue of the Drosophila toll protein. The human TLR4 is a type-1 transmembrane protein containing 799 amino acid residues. The extracellular domain has leucine-rich repeats and the intracellular domain is similar to that of IL-1 receptor. TLR4 is a receptor for lipopolysaccharide (LPS). In mice that are genetically tolerant to endotoxin, mutations have been identified in the intracellular domain of TLR4 that abolish LPS responsiveness. TLR4 uses a mechanism similar to that of the IL-1 receptor for signal transduction that leads to activation of NF-kB.
  • Reactivity
    Rat
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203