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anti-CD3 antibody [1F4]

ARG23315
Arigo Biolaboratories
ApplicationsFlow Cytometry, ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityRat
TargetCd3g
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-CD3 antibody [1F4]
  • Delivery Days Customer
    23
  • Applications
    Flow Cytometry, ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    1F4
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID300678
  • Target name
    Cd3g
  • Target description
    CD3g molecule
  • Target synonyms
    CD3 antigen, gamma polypeptide; CD3 gamma-chain; CD3 molecule, gamma polypeptide; T-cell receptor T3 gamma chain; T-cell surface glycoprotein CD3 gamma chain
  • Host
    Mouse
  • Isotype
    IgM
  • Scientific Description
    The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
  • Reactivity
    Rat
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203