Bio-Connect

anti-CD3 antibody [CA17.2A12]

ARG22833
Arigo Biolaboratories
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityCanine
TargetCD3E
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-CD3 antibody [CA17.2A12]
  • Delivery Days Customer
    23
  • Applications
    Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    CA17.2A12
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID442981
  • Target name
    CD3E
  • Target description
    CD3e molecule
  • Target synonyms
    CD3 epsilon; CD3E antigen, epsilon polypeptide (TiT3 complex); T-cell surface glycoprotein CD3 epsilon chain
  • Host
    Mouse
  • Isotype
    IgG1
  • Scientific Description
    The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
  • Reactivity
    Canine
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203