anti-CD3 antibody [CA17.2A12] (FITC)
ARG22832
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityCanine
TargetCD3E
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-CD3 antibody [CA17.2A12] (FITC)
- Delivery Days Customer23
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDCA17.2A12
- Concentration0.1 mg/ml
- ConjugateFITC
- Gene ID442981
- Target nameCD3E
- Target descriptionCD3e molecule
- Target synonymsCD3 epsilon; CD3E antigen, epsilon polypeptide (TiT3 complex); T-cell surface glycoprotein CD3 epsilon chain
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThe protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
- ReactivityCanine
- Storage Instruction2°C to 8°C
- UNSPSC12352203