anti-CD3 antibody [CT-3] (APC)

Arigo Biolaboratories

anti-CD3 antibody [CT-3] (APC)

23

Flow Cytometry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

CT-3

0.1 mg/ml

APC (Allophycocyanin)

CD3D

CD3d molecule

CD3; CD3 glycoprotein; CD3 type I transmembrane glycoprotein; CD3D antigen delta; CD3D antigen, delta polypeptide (TiT3 complex); CD3d molecule, delta (CD3-TCR complex); T-cell surface glycoprotein CD3 delta chain; T-cell surface protein

Mouse

IgG1

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.

Chicken

2°C to 8°C

12352203