anti-CD3 antibody [KT3] (APC)

Arigo Biolaboratories

anti-CD3 antibody [KT3] (APC)

23

Flow Cytometry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen

Research Use Only

Monoclonal

KT3

APC (Allophycocyanin)

Cd3g

CD3 antigen, gamma polypeptide

Ctg3; Ctg-3; T3g; T-cell receptor T3 gamma chain; T-cell surface glycoprotein CD3 gamma chain

Rat

IgG2a

CD3 (cluster of differentiation 3) is a protein complex and T cell co-receptor that is involved in activating both the cytotoxic T cell (CD8+ naive T cells) and T helper cells (CD4+ naive T cells). It is composed of four distinct chains. In mammals, the complex contains a CD3gamma chain, a CD3delta chain, and two CD3epsilon chains. These chains associate with the T-cell receptor (TCR) and the CD3-zeta (aeta-chain) to generate an activation signal in T lymphocytes. The TCR, CD3-zeta, and the other CD3 molecules together constitute the TCR complex.

Mouse

2°C to 8°C

12352203