Anti-CD31 [JC70]

Absolute Antibody

Anti-CD31 [JC70]

7

This antibody recognises CD31 (PECAM1) which is a member of the immunoglobulin superfamily and is expressed at various circulatng cells, such as neutrophils, monocytes, platelets as well as on endothelial cells. CD31 is a cell adhesion molecule and is inv

This antibody recognises CD31 which is widely expressed on endothelial cells (Parums et al., 1990) and JC70 is a good marker of endothelial cells in paraffin sections. It may be used in the identification and characterisation of benign and malignant human vascular disorders (Parums et al., 1990). For instance, one group utilised this antibody to analyse formalin-fixed paraffin-embedded rat heart tissue in a study investigating relation between cisplatin and oxidative stress (Stojic et al., 2018). Similarly, another group labelled pancreatic tumour tissue samples against CD31 while studying factors influencing development of pancreatic cancer-associated thrombosis (Woei-A-Jin et al., 2016). Finally, Kandemir and colleagues (2012) stained formalin-fixed and paraffin-embedded samples of cutaneous Kaposi sarcoma in order to characterise its immunohistochemical profile.

Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoHistoChemistry

IHC; IF; FACS; WB

Research Use Only

Monoclonal

JC70

PECAM1

platelet and endothelial cell adhesion molecule 1

CD31; CD31 antigen; CD31/EndoCAM; endoCAM; GPIIA'; PECA1; PECAM-1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1

Human

IgG1

Platelet endothelial cell adhesion molecule

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Human, Mouse, Rabbit

Human, Mouse, Rabbit

This antibody was raised by immunising Balb/c mice with membrane preparation from a spleen affected by hairy cell leukaemia.

-20°C,2°C to 8°C

12352203