Flow Cytometry: Human peripheral blood lymphocytes stained with ARG65561 anti-CD33 antibody [WM53] (FITC) and ARG21260 anti-CD19 antibody [SJ25-C1] (PE).
Flow Cytometry: Human peripheral blood lymphocytes stained with ARG65561 anti-CD33 antibody [WM53] (FITC) and ARG21260 anti-CD19 antibody [SJ25-C1] (PE).
anti-CD33 antibody [WM53] (FITC)
ARG65561
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, Neutralisation/Blocking
Product group Antibodies
ReactivityHuman
TargetCD33
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-CD33 antibody [WM53] (FITC)
- Delivery Days Customer23
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, Neutralisation/Blocking
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDWM53
- ConjugateFITC
- Gene ID945
- Target nameCD33
- Target descriptionCD33 molecule
- Target synonymsCD33 antigen (gp67); CD33 molecule transcript; gp67; myeloid cell surface antigen CD33; p67; sialic acid-binding Ig-like lectin 3; SIGLEC3; SIGLEC-3
- HostMouse
- IsotypeIgG1
- Scientific DescriptionCD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies; these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia.
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203