Anti-CD37 [IPO-24 (ZC37-24)]

Absolute Antibody

Anti-CD37 [IPO-24 (ZC37-24)]

9

This antibody recognizes CD37, which is a cell surface protein, present mostly on mature B cells and B cell malignancies.

This antibody is recommended for the analysis and detection of B cells and their malignancies as CD37 is a valuable and stable marker for peripheral mature B-cells and corresponding malignancies, such as B-cell chronic lymphocytic leukemia (B-CLL), hairy cell leukemia (HCL), and all types of B-cell non-Hodgkins lymphoma (B-NHL). Consequently, this antibody might be useful for the treatment of B cell malignancies and autoimmune and inflammatory diseases that involve B cells in their pathology. Finally, IPO-24 antibody, might be used to identify CD37 via various techniques. For instance, it was used to evaluate CD37 expression in mantle cell lymphoma samples via immunohistochemistry (Leshchenko et al., 2010).

Flow Cytometry, ImmunoFluorescence, ImmunoHistoChemistry

Research Use Only

Monoclonal

IPO-24 (ZC37-24)

CD37

CD37 molecule

cell differentiation antigen 37; GP52-40; leukocyte antigen CD37; leukocyte surface antigen CD37; tetraspanin-26; TSPAN26; tspan-26

Human

IgG1

Leukocyte antigen CD37

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2b format, for improved compatibility with existing reagents, assays and techniques.

Human

-20°C,2°C to 8°C

12352203