Anti-CD4 [OX-35]

Absolute Antibody

Anti-CD4 [OX-35]

7

OX-35 shows specificity towards rat CD4 antigen. W3/25 and OX-36 bind to different epitopes on CD4 antigen. CD4 is an accessory protein for MHC class-II antigen/T-cell receptor interaction and is involved in regulation of T-cell activation.

This antibody is able to label cells expressing CD4 on their surface and can precipitate CD4 from detergent extracts of radioactively labelled thymocytes.

Functional Assay, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry

WB; ELISA; IHC; IF; IP; functional

Research Use Only

Monoclonal

OX-35

Cd4

Cd4 molecule

CD4 antigen; p55; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; W3/25; W3/25 antigen

Rat

IgG2b

T-cell surface glycoprotein CD4

This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Rat

Rat

OX-35 was prepared by immunizing mice with T blasts prepared in mixed lymphocyte reactions with purified rat T helper cells against irradiated spleen.

-20°C,2°C to 8°C

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