Bio-Connect

Anti-CD4 [OX-68]

Research Use Only
Ab00587-2.0
Absolute Antibody
ApplicationsFlow Cytometry, ImmunoPrecipitation, Western Blot, Other Application
Product group Antibodies
ReactivityRat
TargetCd4
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Absolute Antibody
  • Product Name
    Anti-CD4 [OX-68]
  • Delivery Days Customer
    7
  • Antibody Specificity
    This antibody is reactive with rat CD4 domain 3 & 4, and is partly competitive with OX-67 & 69.
  • Application Supplier Note
    This antibody binds to rat CD4. Upon challenge with HIV-1, this antibody was able to significantly inhibit viral entry into HeLa cells expressing a mutant of rat CD4 that binds gp120 (SImon, 1997). Similarly, pre-binding of gp120 resulted in a 50% reduction in binding of this antibody, indicating epitope masking. Analogous effects on viral entry and synctium formation are observed with MAbs against human CD4.
  • Applications
    Flow Cytometry, ImmunoPrecipitation, Western Blot, Other Application
  • Applications Supplier
    FC; WB; IP; SPR; binding assay
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    OX-68
  • Gene ID24932
  • Target name
    Cd4
  • Target description
    Cd4 molecule
  • Target synonyms
    CD4 antigen; p55; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; W3/25; W3/25 antigen
  • Host
    Mouse
  • Isotype
    IgG2a
  • Protein IDP05540
  • Protein Name
    T-cell surface glycoprotein CD4
  • Reactivity
    Rat
  • Reactivity Supplier
    Rat
  • Reactivity Supplier Note
    This antibody was prepared by subcutaneously injecting BALB/c mice with a soluble form of rat CD4, consisting of domains 3 and 4. A boost of a mixture of free sCD4 and sCD4 bound to cells was administered intravenously.
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203