Anti-CD4 [YKIX302.9]
Ab00594-23.0
ApplicationsFlow Cytometry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityCanine
TargetCD4
Overview
- SupplierAbsolute Antibody
- Product NameAnti-CD4 [YKIX302.9]
- Delivery Days Customer7
- Antibody SpecificityThis antibody is specific for the canine CD4 cell surface antigen, which, in contrast to other mammals, is expressed by neutrophils as well as lymphocyte subsets.
- Application Supplier NoteThis antibody recognizes canine CD4, which binds MHC II, and has been shown to block MHC II-dependent T cell responses in vivo and in vitro. In a canine transplant model, administration of this antibody has been demonstrated to partially deplete circulating T lymphocytes, but alone was not sufficient to prolong allograft survival (Watson, 1993). This antibody is one of a panel of anti-canine monoclonal antibodies can be used in the evaluation of leukemic status in dogs. This antibody has been used in IF and IP analysis to identify the canine homologue of human CD4 (Cobbold, 1994).
- ApplicationsFlow Cytometry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
- Applications SupplierFC; IHC; IHC-fr
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDYKIX302.9
- Gene ID403931
- Target nameCD4
- Target descriptionCD4 molecule
- Target synonymsCD4 antigen (p55); T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4
- HostRabbit
- IsotypeIgG
- Protein IDP33705
- Protein NameT-cell surface glycoprotein CD4
- Scientific DescriptionThis chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.
- ReactivityCanine
- Reactivity SupplierDog
- Reactivity Supplier NoteThis antibody was prepared by immunizing rats with concanavilin A activated T-cell blasts
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203