Anti-CD44 [Hermes -3]

Absolute Antibody

Anti-CD44 [Hermes -3]

7

This antibody is specific for CD44 (gp90 epitope cluster III). Hermes-3 recognizes Hermes antigen homologues on monkey, goat, and sheep lymphocytes.

This antibody has been used in IF, IHC (immunoperoxidase method), cross-blocking and WB studies to characterise the Hermes-defined antigens (Picker, 1989). This antibody is able to block lymphocyte binding to mucosal HEV, without affecting binding to HEV in peripheral lymph nodes and synovium (Jalkanen, 1987). H3-51 is cross-blocked by this antibody, indicating that the epitopes recognized by these two antibodies overlap (Picker, 1989).

Flow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, Neutralisation/Blocking

Blocking; western blot; IHC; IF; FC; ICC; ELISA

Research Use Only

Monoclonal

Hermes -3

CD44

CD44 molecule (Indian blood group)

CD44 antigen; CDW44; cell surface glycoprotein CD44; chondroitin sulfate proteoglycan 8; CSPG8; ECMR-III; epican; extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor; HCELL; hematopoietic cell E- and L-selectin ligand; heparan sulfate proteoglycan; Hermes antigen; homing function and Indian blood group system; HUTCH-I; hyaluronate receptor; IN; Indian blood group antigen; LHR; MC56; MDU2; MDU3; MIC4; Pgp1; phagocytic glycoprotein 1; soluble CD44

Human

IgG1

CD44 antigen

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Human

Human

This antibody was produced by immunizing BALB/c mice with purified Hermes-1 antigen from KCA, a human B lymphoblastoid line that binds preferentially to mucosal HEV.

-20°C,2°C to 8°C

12352203