Anti-CD47 [105D11]

Absolute Antibody

Anti-CD47 [105D11]

9

This antibody binds the extracellular domain of the human CD47 and cross reacts with cynomolgus monkey CD47. CD47 is broadly distributed on normal adult tissues, as well as ovarian tumors, and is especially abundant in some epithelia and the brain. IAP or

The binding characterization of this antibody to recombinant human Cd47-mFc fusion protein was done using ELISA. This antibody could also bind human and cynomolgus monkey CD47 expressed on the surface of cells in a flow cytometric assay. This antibody was also reported to block the binding between SIRPalpha-hFc protein and human CD47 expressed on the cell surface (CN110724672).

Flow Cytometry, ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

105D11

CD47

CD47 molecule

antigen identified by monoclonal antibody 1D8; antigenic surface determinant protein OA3; CD47 antigen (Rh-related antigen, integrin-associated signal transducer); CD47 glycoprotein; IAP; integrin associated protein; integrin-associated signal transducer; leukocyte surface antigen CD47; MER6; OA3; Rh-related antigen

Human

IgG1

Leukocyte surface antigen CD47

Human, Monkey

-20°C,2°C to 8°C

12352203