Bio-Connect

Anti-CD48 [OX-45]

Research Use Only
Ab00571-8.4
Absolute Antibody
ApplicationsFlow Cytometry, Neutralisation/Blocking
Product group Antibodies
ReactivityRat
TargetCd48
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Overview

  • Supplier
    Absolute Antibody
  • Product Name
    Anti-CD48 [OX-45]
  • Delivery Days Customer
    7
  • Antibody Specificity
    OX-45 binds specifically to CD48 on rat thymocytes, T and B cells and endothelium but not LFA.3. Directly competes with CD46 for binding the target epitope. CD48 is a CD2 ligand and is expressed on the surface of all hematopoietic cells and endothelium. M
  • Application Supplier Note
    Describes the use of OX-45 in blocking the primary mixed lymphocyte response (MLR)and the secondary response of T lymphocytes to the soluble antigen DNP-BGG. It also showed that OX-45 did not have any effect on the cytotoxic activity of specific (CTL) or non-specific (NK) killer cells or on proliferative responses stimulated by lectins or oxidative mitogenesis.
  • Applications
    Flow Cytometry, Neutralisation/Blocking
  • Applications Supplier
    blocking; FC
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    OX-45
  • Gene ID245962
  • Target name
    Cd48
  • Target description
    Cd48 molecule
  • Target synonyms
    BCM1 surface antigen; BLAST-1; CD48 antigen; MRC OX-45 surface antigen; signaling lymphocytic activation molecule 2; SLAM family member 2; SLAMF2
  • Host
    Rat
  • Isotype
    IgG2b
  • Protein IDP10252
  • Protein Name
    CD48 antigen
  • Scientific Description
    This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
  • Reactivity
    Rat
  • Reactivity Supplier
    Rat
  • Reactivity Supplier Note
    OX-45 was prepared by immunizing BALB/c mice with rat T blasts prepared by stimulating purified T helper (TH) cells with allogeneic irradiated rat spleen cells.
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203