Bio-Connect

Anti-CD5 [5D7]

AB04160-10.3-BT
Absolute Antibody
ApplicationsFunctional Assay, Flow Cytometry
Product group Antibodies
ReactivityHuman, Monkey
TargetCD5
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Overview

  • Supplier
    Absolute Antibody
  • Product Name
    Anti-CD5 [5D7]
  • Delivery Days Customer
    9
  • Antibody Specificity
    This antibody binds human CD5, which is a surface glycoprotein that act as a receptor in regulating T-cell proliferation. CD5 is a good immunohistochemical marker for T-cells. This antibody also cross reacts with cynomolgus monkey CD5.
  • Application Supplier Note
    The binding of this antibody to human and cynomolgus monkey PBMCs was studied using flow cytometry. The human IgG1 version of this antibody mediates significant ADCC activity against the CLL cell line Wac3CD5, using purified NK cells as effector cells. Anti-RSV IgGI was used as an isotype control. In a caspase activity assay this antibody showed capability of inhibiting survival of both CLL and ALCL tumor cells by mediating apoptosis against these cells. Humanized version of this antibody is available on request (US20080254027).
  • Applications
    Functional Assay, Flow Cytometry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    5D7
  • Gene ID921
  • Target name
    CD5
  • Target description
    CD5 molecule
  • Target synonyms
    CD5 antigen (p56-62); epididymis secretory sperm binding protein; LEU1; lymphocyte antigen T1/Leu-1; T1; T-cell surface glycoprotein CD5
  • Host
    Human
  • Isotype
    IgG1
  • Protein IDP06127
  • Protein Name
    T-cell surface glycoprotein CD5
  • Scientific Description
    This is a reformatted human IgG1 Fc Silent™ antibody, based on the original human IgG1 format, created for improved compatibility with existing reagents, assays and techniques.
  • Reactivity
    Human, Monkey
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203