Anti-CD50 [186 2G9], Mouse IgG2b, Fc Silent(tm), kappa

Absolute Antibody

Anti-CD50 [186 2G9], Mouse IgG2b, Fc Silent(tm), kappa

9

This antibody is specific for human CD50.

The original version of this antibody was used to immunophenotype mast cells through flow cytometry, while studying the cell surface markers of human skin mast cells. (Ghannadan et al., 1998; PMID:9764855). This antibody was used to block CD50, to determine the effect of the CD50 protein on PMN attachment (Sudina et al., 2001; PMID:11672437). This antibody was able to stain CD50 in a immunohistochemistry experiment on psoriasis tissue. This experiment was performed to study the mechanism of action of methotrexate (Yazici et al., 2005; PMID:16215763).

Flow Cytometry, Neutralisation/Blocking

Research Use Only

Monoclonal

186 2G9

ICAM3

intercellular adhesion molecule 3

CD50; CDW50; ICAM-3; ICAM-R; intercellular adhesion molecule 3

Mouse

IgG2b

Intercellular adhesion molecule 3

This is a reformatted mouse IgG2b Fc Silent™ antibody, based on the original mouse IgG2b format, created for improved compatibility with existing reagents, assays and techniques.

Human

-20°C,2°C to 8°C

12352203