Anti-CD53 [HD77]

Absolute Antibody

Anti-CD53 [HD77]

9

This antibody is specific for the extracytoplasmic part of human CD53, a pan-leukocyte antigen.

This antibody has applications in the detection of normal and neoplastic white blood cells. This antibody has been used to stain tumour and mononuclear cells for CD53 expression in flow cytometric analysis of samples from ovarian carcinoma patients (Marme et al, 2002), and cells of the colon carcinoma line HT29 (Koretz et al, 1992). In immunohistochemical analysis of frozen tissue sections, this antibody has been shown to react with osteoclasts and osteoclast-like giant cells in malignant fibrous histiocytoma and in benign giant cell tumor of tendon sheath (Mechtersheimer et al, 1990). This antibody has been used to re-immunoprecipitate CD53 from PKCalpha immunoprecipiates (Zhang et al, 2001).

Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry

Research Use Only

Monoclonal

HD77

CD53

CD53 molecule

antigen MOX44 identified by monoclonal antibody MRC-OX44; CD53 antigen; CD53 glycoprotein; CD53 tetraspan antigen; cell surface antigen; cell surface glycoprotein CD53; leukocyte surface antigen CD53; MOX44; tetraspanin-25; transmembrane glycoprotein; TSPAN25; tspan-25

Human

IgG1

Leukocyte surface antigen CD53

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Human

-20°C,2°C to 8°C

12352203