Anti-CD56 [N901]

Absolute Antibody

Anti-CD56 [N901]

7

This antibody binds CD56, present on large granular lymphocytes including natural killer cells. This antibody does not react with monocytes, granulocytes, B cells, erythrocytes, or platelets.

This antibody does not block the natural killer cell activity and can be used to rapidly purify functional NK cells (PMID:6574190). This antibody was able to precipitate a band at approx. 200-250 kdalton protein in a immunoprecipitation assay. This antibody successfully blocked the binding of anti-NKH1A antibody in an indirect immunofluorescence assay (PMID:3884668). This antibody is also recommended to be used in the study of cell surface antigens of the natural cells (PMID: 3875369). Conjugate of DC1 with murine and humanizsed versions of N901 was found to be potent and effective in selective killing of target cells in culture (PMID: 7545085). THis antibody can also be used for the separation of natural killer cells in a flow cytometry (PMID: 15985539).

Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation

IP; IF; FC

Research Use Only

Monoclonal

N901

NCAM1

neural cell adhesion molecule 1

antigen recognized by monoclonal antibody 5.1H11; CD56; MSK39; NCAM; neural cell adhesion molecule 1; neural cell adhesion molecule, NCAM

Rabbit

IgG

Neural cell adhesion molecule 1

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Human

Human

The original antibody was generated by immunizing mice with human chronic myelogenous leukemia (CML) cells.

-20°C,2°C to 8°C

12352203