anti-CD56 / NCAM antibody [MEM-188]

Arigo Biolaboratories

anti-CD56 / NCAM antibody [MEM-188]

23

Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

MEM-188

1 mg/ml

Unconjugated

>95%

NCAM1

neural cell adhesion molecule 1

antigen recognized by monoclonal antibody 5.1H11; CD56; MSK39; NCAM; neural cell adhesion molecule 1; neural cell adhesion molecule, NCAM

Mouse

IgG2a

CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of immunoglobulin family serving as adhesive molecule which is ubiquitously expressed in nervous system, usually as 120 kDa, 140 kDa or 180 kDa isoform, and it is also found on T cells and NK cells. Polysialic modification results in reduction of CD56-mediated cell adhesion and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumours and ovarian granulosa cell tumours.

Human

-20°C

12352203