Anti-CD6 [OX-52]

Absolute Antibody

Anti-CD6 [OX-52]

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This antibody is specific for rat CD6, which is largely restricted to cells of the T-lymphocyte lineage.

This antibody recognizes rat CD6, which is largely restricted to cells of the T-lymphocyte lineage, and, as a result, this antibody can be used to identify such cells in tissues or cell suspensions (Robinson, 1986). In cell suspensions prepared from lymph node, TDL, thymus and spleen, exclusively T cells are labelled. Using the immunoperoxidase technique on cryostat tissue sections, staining is mainly confined to the T-cell areas of the spleen, lymph nodes and Peyers patches, as well as all thymocytes. However, occassional positive cells have been observed in the B cell areas of lymphoid organs (Robinson, 1986), and consequently this antibody is used in conjunction with other markers, such as OX-19, to identify T cells.

Flow Cytometry, ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen

FC; IHC-fr; IP

Research Use Only

Monoclonal

OX-52

Cd6

Cd6 molecule

CD6 antigen, Tp120; OX52; T-cell differentiation antigen CD6; T-cell differentiation antigen CD6-like

Rat

IgG2b

CD6 antigen

This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Rat

Rat

This antibody was prepared by immunizing BALB/c mice intraperitoneally with 4x10^7 rat (PVG-RT1c) thoracic duct leucocytes, followed 10 days later by a second injection of 4x 10^7 PVG-RT1c spleen cells.

-20°C,2°C to 8°C

12352203