Bio-Connect

Anti-CD62E [CY1788], Human IgG4, kappa

AB04581-13.0-BT
Absolute Antibody
ApplicationsELISA, Neutralisation/Blocking, Other Application
Product group Antibodies
ReactivityHuman
TargetSELE
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Overview

  • Supplier
    Absolute Antibody
  • Product Name
    Anti-CD62E [CY1788], Human IgG4, kappa
  • Delivery Days Customer
    9
  • Antibody Specificity
    This antibody is specific for E-selectin. E-selectin is a cell surface receptor that mediates the binding of neutrophils, monocytes, and some types of memory T cells to the endothelial cells that line blood vessels.
  • Application Supplier Note
    The original version of this antibody (human IgG4) was generated, and its binding efficiency to a soluble form of E-selectin was compared to that of the parental mouse antibody via competitive ELISA. It demonstrated 65% of the binding efficiency of the parental clone. Additionally, this antibody inhibited the in vitro binding of human neutrophils to activated human umbilical vein endothelial cells (HUVECs) in vitro as effectively as the parental antibody (WO1996040942A1).
  • Applications
    ELISA, Neutralisation/Blocking, Other Application
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    CY1788
  • Gene ID6401
  • Target name
    SELE
  • Target description
    selectin E
  • Target synonyms
    CD62 antigen-like family member E; CD62E; ELAM; ELAM1; ELAM-1; endothelial adhesion molecule 1; endothelial leukocyte adhesion molecule 1; ESEL; E-selectin; LECAM2; leukocyte endothelial cell adhesion molecule 2
  • Host
    Human
  • Isotype
    IgG4
  • Protein IDP16581
  • Protein Name
    E-selectin
  • Reactivity
    Human
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203