Anti-CD62E [CY1788], Human IgG4, kappa

Absolute Antibody

Anti-CD62E [CY1788], Human IgG4, kappa

9

This antibody is specific for E-selectin. E-selectin is a cell surface receptor that mediates the binding of neutrophils, monocytes, and some types of memory T cells to the endothelial cells that line blood vessels.

The original version of this antibody (human IgG4) was generated, and its binding efficiency to a soluble form of E-selectin was compared to that of the parental mouse antibody via competitive ELISA. It demonstrated 65% of the binding efficiency of the parental clone. Additionally, this antibody inhibited the in vitro binding of human neutrophils to activated human umbilical vein endothelial cells (HUVECs) in vitro as effectively as the parental antibody (WO1996040942A1).

ELISA, Neutralisation/Blocking, Other Application

Research Use Only

Monoclonal

CY1788

SELE

selectin E

CD62 antigen-like family member E; CD62E; ELAM; ELAM1; ELAM-1; endothelial adhesion molecule 1; endothelial leukocyte adhesion molecule 1; ESEL; E-selectin; LECAM2; leukocyte endothelial cell adhesion molecule 2

Human

IgG4

E-selectin

Human

-20°C,2°C to 8°C

12352203