Anti-CD64 [H22]

Absolute Antibody

Anti-CD64 [H22]

9

This antibody binds human CD64 and can be bound to a toxin so that together it displays specific cytotoxicity, and thus can be used to selectively eliminate AML cells; FC analysis indicated that this immunotoxin drove 41% of primary leukemia cells from a patient with CD64-positive AML into early apoptosis (Tur, 2003). Similarly, in an in vivo mouse model, IHC analysis revealed efficient elimination of human CD64+ tumor cells in mouse organs (Tur, 2011).

Flow Cytometry, ELISA, Other Application

Research Use Only

Monoclonal

H22

FCGR1A

Fc gamma receptor Ia

CD64, CD64A, FCG1, FCGR1, FCRI, FcgammaRI, IGFR1, high affinity immunoglobulin gamma Fc receptor I, Fc fragment of IgG receptor Ia, Fc fragment of IgG, high affinity Ia, receptor (CD64), Fc fragment of IgG, high affinity Ia, receptor for (CD64), Fc-gamma RI, Fc-gamma receptor I A1, IgG Fc receptor I, fc-gamma RIA, fcgammaRIa

Human

IgG1

High affinity immunoglobulin gamma Fc receptor I

This is a reformatted Fc Silent™ antibody based on the original Human IgG1 antibody, created for improved compatibility with existing reagents, assays, and techniques.

Human

-20°C,2°C to 8°C

12352203