anti-CD68 antibody [ED1] (Biotin)
ARG23385
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityRat
TargetCd68
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-CD68 antibody [ED1] (Biotin)
- Delivery Days Customer23
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Frozen
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDED1
- Concentration0.1 mg/ml
- ConjugateBiotin
- Gene ID287435
- Target nameCd68
- Target descriptionCd68 molecule
- Target synonymsCD68 antigen; macrosialin
- HostMouse
- IsotypeIgG1
- Scientific DescriptionCD68 is a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]
- ReactivityRat
- Storage Instruction2°C to 8°C
- UNSPSC12352203