anti-CD68 (human), Rabbit Monoclonal (RM496)

RevMAb Biosciences

anti-CD68 (human), Rabbit Monoclonal (RM496)

10

Research Use Only

Monoclonal

CD68 [Macrosialin; GP110; SCARD1] is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML) and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several acute myeloid leukemia studies. - Recombinant Antibody. This antibody reacts to human CD68. Isotype: Rabbit IgG. Immunogen: Recombinant human CD68. Application: IHC, WB. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. CD68 [Macrosialin; GP110; SCARD1] is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML) and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several acute myeloid leukemia studies.

-20°C,2°C to 8°C

12352203