Immunohistochemical staining of formalin-fixed and paraffin-embedded human tonsil tissue sections using anti-CD68 rabbit monoclonal antibody (clone RM496) at a 1:500 dilution.
Immunohistochemical staining of formalin-fixed and paraffin-embedded human tonsil tissue sections using anti-CD68 rabbit monoclonal antibody (clone RM496) at a 1:500 dilution.
anti-CD68 (human), Rabbit Monoclonal (RM496)
REV-31-1388-00
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetCD68
Overview
- SupplierRevMAb Biosciences
- Product Nameanti-CD68 (human), Rabbit Monoclonal (RM496)
- Delivery Days Customer10
- Antibody SpecificityThis antibody reacts to human CD68.
- ApplicationsWestern Blot, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDRM496
- Gene ID968
- Target nameCD68
- Target descriptionCD68 molecule
- Target synonymsCD68 antigen; GP110; LAMP4; macrophage antigen CD68; macrosialin; SCARD1; scavenger receptor class D, member 1
- HostRabbit
- IsotypeIgG
- Protein IDP34810
- Protein NameMacrosialin
- Scientific DescriptionCD68 [Macrosialin; GP110; SCARD1] is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML) and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several acute myeloid leukemia studies. - Recombinant Antibody. This antibody reacts to human CD68. Isotype: Rabbit IgG. Immunogen: Recombinant human CD68. Application: IHC, WB. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. CD68 [Macrosialin; GP110; SCARD1] is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML) and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several acute myeloid leukemia studies.
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203