Anti-CD68 [Y-2/131/47]

Absolute Antibody

Anti-CD68 [Y-2/131/47]

7

This antibody recognises human CD68 antigen. CD68 is a membrane glycoprotein highly expressed in monocytes and macrophages. It is involved in phagocytosis, lysosomal metabolism and interactions with pathogens and other cells.

IP: Y-2/131/47 antibody was used for immunoprecipitation from the material from spleen membranes (Micklem et al., 1989). ICC: This antibody was also used in immunocytochemical staining of acute promyelocytic leukaemia cells in order to establish a characteristic phenotype of the diseased cells and develop a potential diagnostic tool of this disorder (Erber et al., 1994).

ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry

IP; ICC; WB

Research Use Only

Monoclonal

Y-2/131/47

CD68

CD68 molecule

CD68 antigen; GP110; LAMP4; macrophage antigen CD68; macrosialin; SCARD1; scavenger receptor class D, member 1

Human

IgG1

Macrosialin

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Human

Human

This antbody was raised by immunising mice with phytohaemagglutinin-activated peripheral blood mononuclear cells.

-20°C,2°C to 8°C

12352203