Anti-CD7 [YTH3.2.6]

Absolute Antibody

Anti-CD7 [YTH3.2.6]

7

This antibody binds CD7.

The fraction of human lymphocyte cells recognised by YTH 3.2 was analysed by flow cytometry, using fluorescein-labelled F(ab)2 fragments of rabbit anti-(rat Ig) to stain the antibody. Binding has also been characterised by ELISA. In preliminary tests, graft rejection in patients with steroid-resistant kidney rejection indicated that graft rejection could be reversed by YTH 3.2 injections (Hale et al, 1985). This antibody has been used to stain T-cell dependent areas in immunohistology (King et al, 1989).

Flow Cytometry, ImmunoFluorescence, ELISA, ImmunoHistoChemistry

IF; FC; ELISA; IHC

Research Use Only

Monoclonal

YTH3.2.6

CD7

CD7 molecule

CD7 antigen (p41); GP40; LEU-9; p41 protein; T-cell antigen CD7; T-cell leukemia antigen; T-cell surface antigen Leu-9; Tp40; TP41

Human

IgG1

T-cell antigen CD7

This chimeric human antibody was made using the variable domain sequences of the original Rat IgG2b format, for improved compatibility with existing reagents, assays and techniques.

Human

Human

The k-secreting myeloma line Y3/Ag1.2.3 was fused with spleen cells from DA rats immunised with normal human lymphocytes.

-20°C,2°C to 8°C

12352203