anti-CD71 / Transferrin Receptor antibody [23D10]
ARG10482
ApplicationsFlow Cytometry, ImmunoFluorescence, ELISA, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetTFRC
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-CD71 / Transferrin Receptor antibody [23D10]
- Delivery Days Customer23
- ApplicationsFlow Cytometry, ImmunoFluorescence, ELISA, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID23D10
- Concentration1.0-2.0 mg/ml
- ConjugateUnconjugated
- Gene ID7037
- Target nameTFRC
- Target descriptiontransferrin receptor
- Target synonymsCD71; IMD46; p90; T9; TFR; TFR1; TR; transferrin receptor protein 1; TRFR
- HostMouse
- IsotypeIgG2b
- Scientific DescriptionThe functions of Transferrin Receptor is: cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site. [Provide by uniprot]
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203