anti-CD71 / Transferrin Receptor antibody [23D10]

Arigo Biolaboratories

anti-CD71 / Transferrin Receptor antibody [23D10]

23

Flow Cytometry, ImmunoFluorescence, ELISA, ImmunoCytoChemistry

Research Use Only

Monoclonal

23D10

1.0-2.0 mg/ml

Unconjugated

TFRC

transferrin receptor

CD71; IMD46; p90; T9; TFR; TFR1; TR; transferrin receptor protein 1; TRFR

Mouse

IgG2b

The functions of Transferrin Receptor is: cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site. [Provide by uniprot]

Human

-20°C

12352203