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anti-CD71 / Transferrin Receptor antibody [23D10]

ARG10482
Arigo Biolaboratories
ApplicationsFlow Cytometry, ImmunoFluorescence, ELISA, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetTFRC
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-CD71 / Transferrin Receptor antibody [23D10]
  • Delivery Days Customer
    23
  • Applications
    Flow Cytometry, ImmunoFluorescence, ELISA, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    23D10
  • Concentration
    1.0-2.0 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID7037
  • Target name
    TFRC
  • Target description
    transferrin receptor
  • Target synonyms
    CD71; IMD46; p90; T9; TFR; TFR1; TR; transferrin receptor protein 1; TRFR
  • Host
    Mouse
  • Isotype
    IgG2b
  • Scientific Description
    The functions of Transferrin Receptor is: cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site. [Provide by uniprot]
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203