anti-CD85j / LIR1 antibody [4F9]

Arigo Biolaboratories

anti-CD85j / LIR1 antibody [4F9]

23

Flow Cytometry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen

Research Use Only

Monoclonal

4F9

1 mg/ml

Unconjugated

LILRB1

leukocyte immunoglobulin like receptor B1

CD85 antigen-like family member J; CD85J; Ig-like transcript 2; ILT2; ILT-2; immunoglobulin heavy chain variable region; leucocyte Ig-like receptor B1; leukocyte immunoglobulin-like receptor subfamily B member 1; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1; LIR1; LIR-1; MIR7; MIR-7; monocyte/macrophage immunoglobulin-like receptor 7; myeloid inhibitory receptor 7; PIRB; PIR-B

Mouse

IgG1

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Human

-20°C

12352203