Anti-CD86 [OX-48]
Ab00569-8.1
ApplicationsFlow Cytometry, ImmunoFluorescence
Product group Antibodies
ReactivityRat
Overview
- SupplierAbsolute Antibody
- Product NameAnti-CD86 [OX-48]
- Delivery Days Customer7
- Antibody SpecificityOX-48 binds specifically to CD86 targets which are present on subsets of T and B blasts, spleen macrophages and polymorphs, peritoneal macrophages, dendritic cells. OX48 does not appear to bind the same epitope of CD86 as 24F (Stephens et al. 2004). CD86
- Application Supplier NoteOX-48 blocks IL-2 production and proliferation of T cells (except when in exponential phase) (Samoza et al. 1990). The antibody can also be used for FC (Stephens et al. 2004), FACS and IPs. Ox-48 has been shown to be able to block binding of CD86 with its ligand CD28.
- ApplicationsFlow Cytometry, ImmunoFluorescence
- Applications SupplierFC; IF
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDOX-48
- HostRat
- IsotypeIgG2b
- Protein IDQ62810
- Protein NameB7-2
- Scientific DescriptionThis chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
- ReactivityRat
- Reactivity SupplierRat
- Reactivity Supplier NoteOX-48 was prepared by immunizing mice with activated rat T cell blasts
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203