anti-CD8b antibody [PPT23] (FITC)
ARG23175
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityPorcine
TargetCD8B
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-CD8b antibody [PPT23] (FITC)
- Delivery Days Customer23
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDPPT23
- Concentration0.1 mg/ml
- ConjugateFITC
- Gene ID396636
- Target nameCD8B
- Target descriptionCD8b molecule
- Target synonymsCD8 antigen beta polypeptide; T-cell surface glycoprotein CD8 beta chain
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThe CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. [provided by RefSeq, May 2010]
- ReactivityPorcine
- Storage Instruction2°C to 8°C
- UNSPSC12352203