Anti-CD9 [10E4], Mouse IgG2b, Fc Silent(tm), kappa

Absolute Antibody

Anti-CD9 [10E4], Mouse IgG2b, Fc Silent(tm), kappa

9

This antibody specifically binds amino acids KEVFDN in the extracellular loop 2 domain (CD9-ECL2) of human CD9. This protein is an intergral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platele

The binding of this antibody to CD9 expressed on different cancer cell lines like 2774 cells, U031 cells, ANBL-6 cells, 293E cells was tested using flow cytometry (US8197809). The epitope characterization of this antibody for fragment of CD9-ECL2 was measured using ELISA. This antibody significantly inhibited invasion of 2774 (ovarian adenocarcinoma cell line) cells and further inhibited migration and proliferation of 2774 cells (US8197809).

Flow Cytometry, ELISA

Research Use Only

Monoclonal

10E4

CD9

CD9 molecule

5H9 antigen; antigen CD9; BA-2/p24 antigen; BTCC-1; CD9 antigen; CD9 antigen (p24); cell growth-inhibiting gene 2 protein; DRAP-27; leukocyte antigen MIC3; MIC3; motility related protein-1; MRP-1; tetraspanin-29; TSPAN29; TSPAN-29

Mouse

IgG2b

CD9 antigen

This is a reformatted mouse IgG2b Fc Silent™ antibody, based on the original mouse scFv format, created for improved compatibility with existing reagents, assays and techniques.

Human

-20°C,2°C to 8°C

12352203