anti-CD98 antibody [MEM-108] (PE)

Arigo Biolaboratories

anti-CD98 antibody [MEM-108] (PE)

23

Flow Cytometry

Research Use Only

Monoclonal

MEM-108

RPE

SLC3A2

solute carrier family 3 member 2

4F2; 4F2 cell-surface antigen heavy chain; 4F2HC; 4T2HC; antigen defined by monoclonal antibody 4F2, heavy chain; antigen identified by monoclonal antibodies 4F2, TRA1.10, TROP4, and T43; CD98; CD98 heavy chain; CD98HC; lymphocyte activation antigen 4F2 large subunit; MDU1; monoclonal antibody 44D7; NACAE; solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2; solute carrier family 3 (amino acid transporter heavy chain), member 2

Mouse

IgG1

CD98 (4F2) is a type II transmembrane glycoprotein which serves as the heavy chain of the heterodimeric amino acid transporters (HATs). CD98, linked to various light chains by disulfide bond, is responsible for cell surface expression and basolateral localization of this transporter complex in polarized epithelial cells and also interacts with beta1 integrins and increases their affinity for ligand. Besides its roles in amino acid transport, CD98 is thus involved in cell fusion and activation. It is implicated in regulation of cellular differentiation, growth and apoptosis.

Human

2°C to 8°C

12352203