Anti-CD98 [EP3-1]

Absolute Antibody

Anti-CD98 [EP3-1]

7

Shown to bind to epitopes of sequences; LLHGDFHAFSAG-GGGC-NH2, LLHGDFH-GGGC-HN2, and FHAFSAG-GGGC-NH2, but showed no reactivity to live HeLa cells by IF.

CD98 may be a target for T or B cell immune responses against tumour cells in cancer patients (Itoh 2008).

ImmunoFluorescence, ImmunoPrecipitation, Other Application

IF; IP; activate

Research Use Only

Monoclonal

EP3-1

SLC7A5

solute carrier family 7 member 5

4F2 light chain; 4F2LC; CD98; CD98 light chain; D16S469E; E16; integral membrane protein E16; large neutral amino acids transporter small subunit 1; LAT1; L-type amino acid transporter 1; MPE16; sodium-independent neutral amino acid transporter LAT1; solute carrier family 7 (amino acid transporter light chain, L system), member 5; solute carrier family 7 (cationic amino acid transporter, y+ system), member 5

Human

IgG1

Large neutral amino acids transporter small subunit 1

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Human

Human

Immunised mice and constructed IgG1 Fab phage display libraries from the spleen cells. CD98-reactive recombinant Fab fragments were retrieved by epitope peptide panning.

-20°C,2°C to 8°C

12352203