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ProductsBack/Anti-CDKN2A/p14ARF Rabbit mAb

Anti-CDKN2A/p14ARF Rabbit mAb

PTM-5302
PTM BIO
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
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Overview

  • Supplier
    PTM BIO
  • Product Name
    Anti-CDKN2A/p14ARF Rabbit mAb
  • Delivery Days Customer
    5
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry Paraffin
  • Applications Supplier
    WB, IHC-P, ICC/IF, IP
  • Category Supplier
    Antibody
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    JRMR-263
  • Conjugate
    Unconjugated
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ8N726
  • Protein Name
    Tumor suppressor ARF
  • Scientific Description
    Capable of inducing cell cycle arrest in G1 and G2 phases. Acts as a tumor suppressor. Binds to MDM2 and blocks its nucleocytoplasmic shuttling by sequestering it in the nucleolus. This inhibits the oncogenic action of MDM2 by blocking MDM2-induced degradation of p53 and enhancing p53-dependent transactivation and apoptosis. Also induces G2 arrest and apoptosis in a p53-independent manner by preventing the activation of cyclin B1/CDC2 complexes. Binds to BCL6 and down-regulates BCL6-induced transcriptional repression.
  • Shelf life instruction
    Stable for 12 months from date of receipt/reconstitution.
  • Reactivity Supplier
    Human
  • Reactivity Supplier Note
    Protein A purified
  • Storage Instruction
    Store at -20°C. Avoid freeze/thaw cycles.
  • UNSPSC
    12352203