anti-CHML antibody (C-term)
ARG55058
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetCHMP2B
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-CHML antibody (C-term)
- Delivery Days Customer23
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID25978
- Target nameCHMP2B
- Target descriptioncharged multivesicular body protein 2B
- Target synonymsALS17; charged multivesicular body protein 2b; CHMP2.5; chromatin modifying protein 2B; DMT1; FTDALS7; vacuolar protein-sorting-associated protein 2-2; VPS2 homolog B; VPS2-2; VPS2B
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203