Anti-Citrulline-Histone H2A (Arg3) Rabbit pAb
PTM-1305
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
Overview
- SupplierPTM BIO
- Product NameAnti-Citrulline-Histone H2A (Arg3) Rabbit pAb
- Delivery Days Customer5
- Antibody SpecificityAnti-Citrulline-Histone H2A (Arg3) Rabbit pAb detects histone H2A only when it is citrullinated at Arg3.
- ApplicationsWestern Blot
- Applications SupplierWB
- Category SupplierAntibody
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- HostRabbit
- IsotypeIgG
- Protein IDP04908
- Protein NameHistone H2A type 1-B/E
- Scientific DescriptionProtein citrullination is an emerging PTM that results from the conversion of peptidyl arginine to peptidyl citrulline. Due to the exchange of an imine for a carbonyl group, this reaction is referred to as deimination. This PTM is catalyzed by the calcium-regulated peptidylarginine deiminases (PAD). Dysregulated PAD expression and aberrant protein citrullination have been implicated in numerous human diseases such as osteosarcoma, colorectal cancer, esophagus cancer and breast cancer.
- Shelf life instructionStable for 12 months from date of receipt/reconstitution.
- ReactivityHuman, Mouse, Rat
- Reactivity SupplierHuman, Mouse, Rat
- Reactivity Supplier NoteProtein A and immunogen affinity purified
- Storage InstructionStore at -20°C. Avoid freeze/thaw cycles.
- UNSPSC12352203