Anti-class I MHC [5H7]
AB02558-10.0-BT
ApplicationsFlow Cytometry, ImmunoPrecipitation, Neutralisation/Blocking
Product group Antibodies
ReactivityHuman
TargetHLA-A
Overview
- SupplierAbsolute Antibody
- Product NameAnti-class I MHC [5H7]
- Delivery Days Customer9
- Antibody SpecificityThis antibody is specific for HLA class I histocompatibility antigen all different chains. Antigen-presenting major histocompatibility complex class I (MHCI) molecule. In complex with B2M/beta 2 microglobulin displays primarily viral and tumor-derived pep
- Application Supplier NoteThe biotinylated antibody was used for a blocking experiment in human PBLs (Smith et al, 1994; pmid:7913109). Flow cytometry was preformed on human PBMC using this antibody (Woodle et al, 1997; pmid:9036961). This antibody was used for immunoprecipitation on C1R and T2. HMy2.C1R (C1R) are HLA-A negative and -B35 low human B-lymphoblastoid cells, and 0.174 X CEMR (T2) are T-B lymphoblastoid hybrid cells that are missing a large region of the MHC, including the genes encoding TAP1 and TAP2 (Dangoria et al, 2002; pmid:11978783).
- ApplicationsFlow Cytometry, ImmunoPrecipitation, Neutralisation/Blocking
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID5H7
- Gene ID3105
- Target nameHLA-A
- Target descriptionmajor histocompatibility complex, class I, A
- Target synonymsHLA class I histocompatibility antigen, A alpha chain; HLA class I histocompatibility antigen, A-1 alpha chain; HLAA; leukocyte antigen class I-A; MHC class I antigen HLA-A heavy chain
- HostHuman
- IsotypeIgG1
- Protein IDP04439
- Protein NameHLA class I histocompatibility antigen, A-3 alpha chain
- Scientific DescriptionThis chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2b format, for improved compatibility with existing reagents, assays and techniques.
- ReactivityHuman
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203