anti-CLEC7A antibody [2A11] (low endotoxin)

Arigo Biolaboratories

anti-CLEC7A antibody [2A11] (low endotoxin)

23

Functional Assay, Flow Cytometry, ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen

Research Use Only

Monoclonal

2A11

1 mg/ml

Unconjugated

Clec7a

C-type lectin domain family 7, member a

beta-; beta-glucan receptor; beta-GR; BG; BGR; Clecsf; Clecsf12; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 12; C-type lectin domain family 7 member A; C-type lectin superfamily member 12; DC-associated C-type lectin 1; dectin; dectin-1; dendritic cell-associated C-type lectin 1

Rat

IgG2b

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008]

Mouse

-20°C

12352203