anti-CLEC7A antibody [GE2] (low endotoxin)

Arigo Biolaboratories

anti-CLEC7A antibody [GE2] (low endotoxin)

23

Functional Assay, Flow Cytometry

Research Use Only

Monoclonal

GE2

1 mg/ml

Unconjugated

CLEC7A

C-type lectin domain containing 7A

beta-glucan receptor; BGR; CANDF4; CD369; CLECSF12; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12; C-type lectin domain family 7 member A; C-type lectin superfamily member 12; DC-associated C-type lectin 1; DECTIN1; dectin-1; dendritic cell-associated C-type lectin-1; lectin-like receptor 1; SCARE2

Mouse

IgG1

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008]

Human

-20°C

12352203