Anti-CLIC5 Alexa Fluor(r) 647

EXBIO

Anti-CLIC5 Alexa Fluor(r) 647

7

Mouse monoclonal antibody CLIC5-02 recognizes CLIC5a, a 32 kDa intracellular protein which associates with proteins of actin complexes. Crossreactivity with CLIC5b was not determined.

Flow cytometry: Recommended dilution: 1-5 microg/ml. Intracellular staining.

Flow Cytometry, Western Blot

Research Use Only

CLIC5-02

0.1 mg/ml

AlexaFluor 647

IgG2b

CLIC5a belongs to the family of chloride intracellular channel (CLIC) proteins, all sharing a highly conserved C terminus and variable N terminus. Human CLIC5 is transcribed in two isoforms, 32 kDa CLIC5a (251 amino acids) and 49 kDa CLIC5b (410 amino acids). These proteins exist in a soluble form and their function as ion channels in vitro has not been fully confirmed in vivo. CLIC5a is a component of complexes of actin, ezrin, and several other actin-associated proteins and is important for functionality of actin-based structures.

Human

2°C to 8°C

12352203