Anti-CNPS [3E5]

Absolute Antibody

Anti-CNPS [3E5]

9

Specifically binds to CNPS.

This antibody binds to Glucuronoxylomannan (GXM), which is the main constituent of the C. neoformans capsule and modulates the inflammatory response of monocytes. In a later study conducted by Yuan et al. 1998 (PMID: 9488395), it was shown that switching the original murine IgG3 antibody to other IgG subtypes, in particular IgG2A, significantly prolonged animal survival in an infection model.

ELISA

Research Use Only

Monoclonal

3E5

Human

This chimeric human antibody was made using the variable domain sequences of the original mouse IgG3 format for improved compatibility with existing reagents, assays and techniques.

Fungus

-20°C,2°C to 8°C

12352203