anti-CRTC2 / TORC2 antibody
ARG42593
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCRTC2
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-CRTC2 / TORC2 antibody
- Delivery Days Customer23
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID200186
- Target nameCRTC2
- Target descriptionCREB regulated transcription coactivator 2
- Target synonymsCREB-regulated transcription coactivator 2; TORC2; TORC-2; transducer of regulated cAMP response element-binding protein (CREB) 2
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the transducers of regulated cAMP response element-binding protein activity family of transcription coactivators. These proteins promote the transcription of genes targeted by the cAMP response element-binding protein, and therefore play an important role in many cellular processes. Under basal conditions the encoded protein is phosphorylated by AMP-activated protein kinase or the salt-inducible kinases and is sequestered in the cytoplasm. Upon activation by elevated cAMP or calcium, the encoded protein translocates to the nucleus and increases target gene expression. Single nucleotide polymorphisms in this gene may increase the risk of type 2 diabetes. A pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2010]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203